Studies on Fluorene Derivatives. IX

Spectroscopic Studies of Dimethylamino Derivatives of Fluorene

2-dimethylamino-9-fluorenol and 2-dimethylamino-9(4'dimethylamino)phenyl-9-fiuorenol in polar solvents in the excited state undergo conformation changes in which two fluorescent isomers are created. The isomers (in the local excited (LE) and charge transfer (CT) configuration) possess separate fluorescence bands, one appearing from the S! (LE) state and the second f rom the intramolecular charg...

Studies on nicotinamide derivatives.

Photodynamic action of protoporphyrin IX derivatives on Trichophyton rubrum.

BACKGROUND Dermatophytes are filamentous keratinophilic fungi. Trichophyton rubrum is a prevalent infectious agent in tineas and other skin diseases. Drug therapy is considered to be limited in the treatment of such infections, mainly due to low accessibility of the drug to the tissue attacked and development of antifungal resistance in these microorganisms. In this context, Photodynamic Therap...

Green electrogenerated chemiluminescence of highly fluorescent benzothiadiazole and fluorene derivatives.

A group of highly fluorescent 2,1,3-benzothiadiazole derivatives (BH0-BH3), including two fluorene derivatives (AB2 and C01) were synthesized and characterized. The electrochemical, spectroscopic, and electrogenerated chemiluminescence (ECL) properties of the compounds were determined. Benzothiadiazole derivatives BH1, BH2, and BH3 show reversible oxidation and reduction waves and produce stron...

Benzylpiperazine derivatives. IX. Structure-antiulcer activity studies of 1-(aminocarbonylalkyl)-4-benzylpiperazine derivatives by the adaptive least-squares method.

Quantitative structure—antiulcer activity relationships of 1-(aminocarbonylalkyl)-4-benzylpiperazine derivatives (I) were analyzed by using the adaptive least-squares (ALS) technique. Discriminant functions show that (1) a bulky amide moiety is disadvantageous, (2) a small number of methylene groups between carbonyl and piperazine is favorable, (3) a substituent which has a large B1 value (or B...